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Male pattern based hair loss (Androgenic alopecia)

Androgenic alopecia is also called male pattern based hair loss or female pattern based hair loss is partial or complete loss of hair specially on the scalp, generally at the front temporal region and vertex of the head. in women it starts from the partition area of the head. in women it more likely occur after the menopause.
                                                fig.- male and female pattern based hair loss

Hair, in addition to the role of cuticle, is important cosmetically for human beings. Hair loss sometimes causes mental illness. Androgenic hair loss is one of the most common types of hair loss, which in men and women, is genetically predisposed, causing hair loss with a specific pattern. Androgenic hair loss, also called androgenetic alopecia, occurs because of the sensitivity
of the field of follicles to androgens.



In men, the frontotemporal regions, or the front and back regions as well as the center of the head, while in women, there is usually hair thinning and spreading without hair strain. 30% of age 30 years and 50% of age 50 year's male are suffering from androgenic alopecia. 

        
                                       

Causes of androgenic alopecia-
There may be different factors that are responsible for causing androgenic alopecia. they are mentioned as

  • It may be heriditary.
  • Hormonal imbalance(testosterone, dihydrotestosterone)
  • Conversion of testosterone into dihydrotestosterone  
  • Improper diet
  • Medical illness

The typical pattern of male hair loss is because of genetic sensitivity to the effects of dihydrotestosterone (DHT) in certain areas of the scalp. Testosterone is converted to its active form, DHT, which induces hair loss and is linked to androgenic receptors in hair follicles, which results in compromised growth phase of the hair cycle. It is believed that DHT shortens the growth stage, or anagen, from a typical period of three to six years to several weeks or months. This causes the hair follicles to shrink gradually, reducing hair production and making hair smoother.


Treatment of androgenic alopecia-
There are different drugs and therapies used for the treatment and management of androgenetic alopecia. 

  1. Medical treatment-  
  • Finasteride (tablet, capsule)
  • Finasteride + minoxidil (solution, lotion and creams)
  • Minoxidil solution (topical solution, lotion)
  • Dutasteride
  • Antiandrogens
  • Cyproterone acetate, Spironolactone, Flutamide
  • Topical ketoconazole
      2. Non-medical treatment (cosmetic aid)
  • Tinted powders
  • Wigs
  • Hairpieces
  • Hair extensions
      3. Surgical treatments
  • Hair transplant
  • Scalp reduction
  • Platelet rich plasma therapy
  • Laser light therapy
  • Scalp flaps
  • Alopecia Reduction (AR)












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